Document Detail


Antimicrobial activity investigation on Wuyiencin fractions of different polarity.
MedLine Citation:
PMID:  20657470     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to evaluate the antimicrobial activity of Wuyiencin fractions with different polarities against six indicator microorganisms: Rhodotorula rubra, Bacillus subtilis, Bacillus megaterium, Escherichia coli, Cladosporium fulvum and Staphylococcus aureus. The fermentation broth of Wuyiencin was submitted to AB-8 macroporous adsorptive resin and fractionated with solvents of different polarity. The fraction eluted with water had remarkably antimicrobial activity against all the microorganisms investigated except for C. fulvum and S. aureus (MIC <or= 0.0625 mg/mL), probably due to the presence of active components. The fraction eluted with methanol showed potential antimicrobial activity against all the test microorganisms except for R.rubra, with MIC values of 0.5 and 2 mg/mL. In conclusion, fractions eluted with water and methanol, respectively, represent the main active-part of Wuyiencin, and could be emphasized for agricultural applications in the future.
Authors:
Zengjie Cui; Kecheng Zhang; Gaimei She; Yinni Lin; Lei Sun; Yan Cheng; Beibei Tan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-29
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  15     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2010-11-03     Revised Date:  2010-12-15    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  3179-85     Citation Subset:  IM    
Affiliation:
State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
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MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents / isolation & purification,  pharmacology*
Bacillus megaterium / drug effects
Bacillus subtilis / drug effects
Chemical Fractionation
Cladosporium / drug effects
Escherichia coli / drug effects
Fermentation
Hydrophobic and Hydrophilic Interactions
Microbial Sensitivity Tests
Plant Extracts / isolation & purification,  pharmacology*
Rhodotorula / drug effects
Staphylococcus aureus / drug effects
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Plant Extracts

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