| Antimicrobial effects of calcium hydroxide and chlorhexidine on Enterococcus faecalis. | |
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MedLine Citation:
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PMID: 20647103 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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INTRODUCTION: Endodontic treatment is commonly based on nonspecific elimination of intraradicular microorganisms. Although some authors prefer single-visit root canal operations for endodontic treatment, several studies have shown the importance of intracanal medication between sessions to kill microorganisms that biomechanical preparations alone cannot achieve. The purpose of this study was to evaluate the efficacy of calcium hydroxide Ca(OH)(2) and chlorhexidine gel on the elimination of intratubular Enterococcus faecalis. METHODS: Human uniradicular teeth contaminated with E. faecalis were treated with Ca(OH)(2), 2% chlorhexidine gel, Ca(OH)(2) plus 2% chlorhexidine gel, or saline (0.9% NaCl) as a negative control. Samples obtained at a depth of 0 to 100 mum and 100 to 200 mum from these root canal preparations were analyzed for bacterial load by counting the number of colony-forming units (CFUs) and bacterial viability using fluorescence microscopy. RESULTS: A significant decrease in the number of CFUs and the percentage of viable E. faecalis was observed after treatment with either Ca(OH)(2) or chlorhexidine when compared with the control group. Additionally, chlorhexidine gel had a significantly higher antimicrobial efficacy as measured by the number of CFUs and the percentage of viable cells than Ca(OH)(2). No differences were observed between the antimicrobial properties of chlorhexidine gel with and without the addition of Ca(OH)(2). CONCLUSION: Both Ca(OH)(2) and chlorhexidine have antimicrobial effects on E. faecalis. Chlorhexidine had increased antimicrobial activity when compared with Ca(OH)(2.) Ca(OH)(2) combined with chlorhexidine showed similar antimicrobial activity to chlorhexidine alone. |
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Authors:
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Ronan J R Delgado; Thaís H Gasparoto; Carla R Sipert; Claudia R Pinheiro; Ivaldo G Moraes; Roberto B Garcia; Clóvis M Bramante; Ana P Campanelli; Norberti Bernardineli |
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Publication Detail:
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Type: Journal Article Date: 2010-06-19 |
Journal Detail:
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Title: Journal of endodontics Volume: 36 ISSN: 1878-3554 ISO Abbreviation: J Endod Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7511484 Medline TA: J Endod Country: United States |
Other Details:
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Languages: eng Pagination: 1389-93 Citation Subset: D |
Copyright Information:
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Copyright 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP 17012-901, Brazil. ronanjacques@hotmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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