Document Detail


Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines.
MedLine Citation:
PMID:  20584608     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on novel 3-arylamino-6-benzylamino-1,2,4,5-tetrazines with potent activity against Plasmodium falciparum.
Authors:
Duong Nhu; Sandra Duffy; Vicky M Avery; Andrew Hughes; Jonathan B Baell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-10
Journal Detail:
Title:  Bioorganic & medicinal chemistry letters     Volume:  20     ISSN:  1464-3405     ISO Abbreviation:  Bioorg. Med. Chem. Lett.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-16     Completed Date:  2010-11-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107377     Medline TA:  Bioorg Med Chem Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  4496-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Antimalarials / chemical synthesis,  chemistry*,  toxicity
Benzylamines / chemical synthesis,  chemistry*,  toxicity
Plasmodium falciparum / drug effects
Structure-Activity Relationship
Tetrazoles / chemical synthesis,  chemistry,  toxicity
Chemical
Reg. No./Substance:
0/Antimalarials; 0/Benzylamines; 0/Tetrazoles

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