Document Detail

Antihypertensive therapy in pregnancy.
MedLine Citation:
PMID:  15529297     Owner:  NLM     Status:  MEDLINE    
The benefits of antihypertensive therapy in pregnancy remain uncertain. Blood pressure control to prevent or correct severe hypertension can avert maternal target organ damage and may allow obstetricians to prolong pregnancy or avoid hospitalization. Several factors limit the conclusions derived from systematic review of the available studies, including failure to distinguish among women with preeclampsia, gestational hypertension, or whose hypertension antedated pregnancy. As well, the application of consensus guidelines is limited by the unfortunate tendency to measure blood pressure by use of oscillometric devices rather than auscultation. We review the basis for using specific antihypertensive drugs in pregnancy and highlight important shortcomings in therapeutic knowledge that should be addressed in future studies.
Tiina Podymow; Phyllis August; Jason G Umans
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Seminars in nephrology     Volume:  24     ISSN:  0270-9295     ISO Abbreviation:  Semin. Nephrol.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-05     Completed Date:  2005-09-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8110298     Medline TA:  Semin Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  616-25     Citation Subset:  IM    
Division of Nephrology and Hypertension, Weill Medical College of Cornell University, New York, NY, USA.
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Hypertension / drug therapy*
Pregnancy Complications, Cardiovascular / drug therapy*
Grant Support
Reg. No./Substance:
0/Antihypertensive Agents

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