| Antihypertensive effect of gamma-amino butyric acid enriched soy products in spontaneously hypertensive rats. | |
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MedLine Citation:
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PMID: 15630275 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of gamma-amino butyric acid (GABA)-enriched soybean on blood pressure was investigated in male spontaneously hypertensive rats. Ten-week-old rats were given diets containing graded levels of GABA-enriched soybean powder for 8 weeks. The systolic blood pressure in rats fed 0.15% GABA diet was significantly lower at 1st week and maintained lower values for 4 weeks as compared with 0% GABA controls. No effect on blood pressure was found in those of 0.03 and 0.3% GABA. The results suggest that there exist appropriate dietary GABA level to get the blood pressure lowering effect. |
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Authors:
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F Shizuka; Y Kido; T Nakazawa; H Kitajima; C Aizawa; H Kayamura; N Ichijo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: BioFactors (Oxford, England) Volume: 22 ISSN: 0951-6433 ISO Abbreviation: Biofactors Publication Date: 2004 |
Date Detail:
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Created Date: 2005-01-04 Completed Date: 2005-04-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807441 Medline TA: Biofactors Country: Netherlands |
Other Details:
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Languages: eng Pagination: 165-7 Citation Subset: IM |
Affiliation:
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Department of Living Sciences, Nagano Prefectural College, 8-49-7 Miwa, Nagano-City, 380-8525, Japan. fujikos@sonata.plala.or.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antihypertensive Agents / pharmacology* Blood Pressure / drug effects* Diet Dietary Supplements Hypertension / drug therapy* Male Rats Rats, Inbred SHR Soybeans* Systole / drug effects gamma-Aminobutyric Acid / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 56-12-2/gamma-Aminobutyric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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