Document Detail

Antihypertensive drugs and central blood pressure.
MedLine Citation:
PMID:  19602325     Owner:  NLM     Status:  In-Process    
Recent evidence suggests that central blood pressure is a more important determinant of cardiovascular risk than brachial pressure. Interestingly, antihypertensive drugs exert different effects on brachial and central pressure. Traditional beta-blockers, such as atenolol, appear to have an adverse impact on central pressure, despite lowering brachial pressure. This may help to explain the results of recent large outcome studies using atenolol. Further research is required to clarify whether other antihypertensive agents lower central pressure beyond the effects observed on brachial pressure.
Carmel M McEniery
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  11     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  253-9     Citation Subset:  IM    
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital Box 110, Cambridge CB20QQ, United Kingdom.
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