| Antihypertensive Drugs and Inflammation in Acute Ischemic Stroke as a Predictor Factor of Future Cardiovascular Mortality. | |
| | |
MedLine Citation:
|
PMID: 21240546 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The beneficial effects of antihypertensive drugs in secondary stroke prevention could not be based on their effects on lowering hypertension only.In this prospective study, the status of blood pressure, treatment regimens, new atherothrombotic event, blood sampling for hs-CRP and fibrinogen were asked at initial visit, 6th, and 12th months in 226 patients with atherothrombotic stroke.Eighty-seven percent of patients had an antihypertensive regimen, but hypertension control was achieved in 34.1% of patients.Neither use of six different antihypertensive drug regimens nor the change in blood pressure levels showed any difference on new atherothrombotic events, outcomes or survival rates.On the other hand, the higher levels of hs-CRP at baseline were found to be associated with higher mortality rates(p = 0.020).Our findings emphasize the predictive role of inflammation in future cardiovascular mortality in patients with acute ischemic stroke, indicating that inflammatory mediators underlying the atherothrombotic process play a more important role than it is assumed. |
| | |
Authors:
|
Gulcin Benbir; Birsen Ince; Emre Kumral; Zeki Ongen; Hakan Kultursay; Lale Tokgozoglu; Ali Oto; Hasan Tuzun; |
Related Documents
:
|
19959536 - Cerebral flow velocities during daily activities depend on blood pressure in patients w... 416666 - Stroke in the africans. 10796286 - Interventions for deliberately altering blood pressure in acute stroke. blood pressure ... 6420026 - Intravenous nitroglycerin administration during infrarenal aortic clamping. 3344076 - Enteral and intranasal treatment for vasopressor-dependent hypotension in c1 tetraplegia. 5338086 - The application of starling's law of capillary exchange to the lungs. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-1-15 |
Journal Detail:
|
Title: Inflammation Volume: - ISSN: 1573-2576 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2011-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7600105 Medline TA: Inflammation Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Cerrahpaşa Faculty of Medicine, Department of Neurology, Istanbul University, 34098, Istanbul, Turkey, drgulcinbenbir@yahoo.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Recombinant scorpion insect excitatory toxin BmK IT accelerates the growth of insect Spodoptera frug...
Next Document: Mobilizing Communities to Implement Evidence-Based Practices in Youth Violence Prevention: The State...