| Antihyperglycemic and Antioxidative Effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in Mice Fed with a High Fat Diet. | |
| | |
MedLine Citation:
|
PMID: 22489179 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The effect of dietary feeding of hydroxyethyl methylcellulose (HEMC) and hydroxypropyl methylcellulose (HPMC) on the glucose metabolism and antioxidative status in mice under high fat diet conditions was investigated. The mice were randomly divided and given experimental diets for six weeks: normal control (NC group), high fat (HF group), and high fat supplemented with either HEMC (HF+HEMC group) or HPMC (HF+HPMC group). At the end of the experimental period, the HF group exhibited markedly higher blood glucose and insulin levels as well as a higher erythrocyte lipid peroxidation rate relative to the control group. However, diet supplementation of HEMC and HPMC was found to counteract the high fat-induced hyperglycemia and oxidative stress via regulation of antioxidant and hepatic glucose-regulating enzyme activities. These findings illustrate that HEMC and HPMC were similarly effective in improving the glucose metabolism and antioxidant defense system in high fat-fed mice and they may be beneficial as functional biomaterials in the development of therapeutic agents against high fat dietinduced hyperglycemia and oxidative stress. |
| | |
Authors:
|
Su Jeong Ban; Catherine W Rico; In Chul Um; Mi Young Kang |
Related Documents
:
|
4031059 - Identification of gallbladder mucin-bilirubin complex in human cholesterol gallstone ma... 3889239 - Digestion and absorption of lipids in poultry. 12832029 - Pancreatic lipase activity as influenced by unconjugated bile acids and ph, measured in... 6293939 - Diet and gall stones: effects of refined and unrefined carbohydrate diets on bile chole... 22701749 - Tumor progression locus 2 (tpl2) deficiency does not protect against obesity-induced me... 22449699 - Anti-obesity and hypolipidemic effects of rheum undulatum in high-fat diet-fed c57bl/6 ... 16136539 - Health consequences of postsocialist transition: dietary and lifestyle determinants of ... 1916459 - Unexpected white matter changes in an early treated pku case and improvement after diet... 12576519 - A low fish oil inhibits srebp-1 proteolytic cascade, while a high-fish-oil feeding decr... |
Publication Detail:
|
Type: Journal Article Date: 2012-03-21 |
Journal Detail:
|
Title: International journal of molecular sciences Volume: 13 ISSN: 1422-0067 ISO Abbreviation: Int J Mol Sci Publication Date: 2012 |
Date Detail:
|
Created Date: 2012-04-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101092791 Medline TA: Int J Mol Sci Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 3738-50 Citation Subset: - |
Affiliation:
|
Department of Food Science and Nutrition, Kyungpook National University, Daegu 702-701, Korea; E-Mails: crystal_hoi@nate.com (S.J.B.); ckwrico@gmail.com (C.W.R.). |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Photosensized controlling benzyl methacrylate-based matrix enhanced eu(3+) narrow-band emission for ...
Next Document: Expression Analysis of Four Peroxiredoxin Genes from Tamarix hispida in Response to Different Abioti...