Document Detail


Antigenic differences between the endometrium of women with and without endometriosis.
MedLine Citation:
PMID:  2030493     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum and peritoneal fluid from 12 women with endometriosis, 4 women with uterine leiomyomata and 6 fertile women without endometriosis (controls) and serum from 4 women with adenomyosis were tested with a passive hemagglutination assay for antibodies against endometrium from all the controls, 8 patients with endometriosis and all patients with uterine leiomyomata and from implants from 8 patients with endometriosis. Serum antibody titers in patients with endometriosis or leiomyomata were significantly higher against endometrial or implant antigens from patients with endometriosis and 2 patients with leiomyomata than those against the controls' endometrium. Peritoneal fluid endometrial antibody titers failed to reflect these antigenic differences. Controls and patients with adenomyosis had low titers of endometrial antibodies in their serum or peritoneal fluid. Antigenic differences appear to exist between the endometrium of patients with endometriosis and that of controls.
Authors:
D Garza; S Mathur; M M Dowd; L F Smith; H O Williamson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  36     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-06-18     Completed Date:  1991-06-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibodies, Neoplasm / analysis*,  blood
Ascitic Fluid / immunology
Autoantibodies / analysis*
Autoimmunity / physiology
Endometriosis / immunology*
Female
Hemagglutination Tests / methods
Humans
Leiomyoma / immunology*
Uterine Neoplasms / immunology*
Chemical
Reg. No./Substance:
0/Antibodies, Neoplasm; 0/Autoantibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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