Document Detail

Antigen dose response and specificity of production of the lymphokine eosinophil stimulation promoter.
MedLine Citation:
PMID:  977995     Owner:  NLM     Status:  MEDLINE    
The present investigations of the recently discovered lymphokine eosinophil stimulation promoter have (1) shown that the assay system is highly sensitive and reproducible via the establishment of dose-response curves and their statistical analysis, (2) demonstrated that the direct assay is specific with use of eosinophilrich peritoneal exudate cells obtained from mice with either schistosomiasis or trichinosis, (3) demonstrated that the indirect test with splenic lymphocytes is specific with use of both the above method and radioisotope-labeled antigens, and (4) provided information on the roles of eosinophils and mononuclear cells via purification, reconstitution, and the use of antiserum to eosinophils.
R P Pelley; R Karp; A A Mahmoud; K S Warren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  134     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-23     Completed Date:  1976-12-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  230-7     Citation Subset:  AIM; IM    
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MeSH Terms
Cell Movement
Eosinophils / immunology*,  physiology
Lymphocytes / immunology
Lymphokines / biosynthesis*
Schistosomiasis / immunology
Spleen / cytology
Statistics as Topic
Reg. No./Substance:
0/Antigens; 0/Lymphokines

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