Document Detail


Antifungal activity of some substituted pyrimidines.
MedLine Citation:
PMID:  24272695     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Several 6-chloro-5-nitropyrimidines were synthesized, and their antifungal activity was tested. Some derivatives were equipotent or superior to amphotericin B in vitro but their relatively high toxicity in mice and their chemical instability discourage further evaluation.
Authors:
J D McChesney; M Gonzalez-Sierra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmaceutical research     Volume:  2     ISSN:  0724-8741     ISO Abbreviation:  Pharm. Res.     Publication Date:  1985 May 
Date Detail:
Created Date:  2013-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406521     Medline TA:  Pharm Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-7     Citation Subset:  -    
Affiliation:
Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi, 38677.
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