| Antifungal abietane-type diterpenes from the cones of Taxodium distichum Rich. | |
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MedLine Citation:
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PMID: 21072573 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The chemical composition of Taxodium distichum cones and the antifungal activities of twelve diterpenoids against two wood decay fungi, Trametes versicolor (white-rot) and Fomitopsis palustris (brown-rot) were examined. The chemical composition of the major extractive fraction, the n-C(6)H(14) extract, was evaluated and its antifungal properties were identified. Twelve diterpenoids including ten abietane-type components were isolated from the n-C(6)H(14) extract: 6,7-dehydroferruginol (1), ferruginol (2), 6,7-dehydroroyleanone (3), sandaracopimaric acid (4), taxodione (5), taxodal (6), taxodone (7), sugiol (8), xanthoperol (9), salvinolone (10), 5,6-dehydrosugiol (11), and 14-deoxycoleon U (12). Compounds 5 and 12 were highly active against both wood-decay fungi. In particular, the activities of these compounds against F. palustris were potent. The results suggest that the position and the number of hydroxyl groups on abietane-type structures may be related to antifungal activities against T. versicolor and F. palustris. |
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Authors:
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Norihisa Kusumoto; Tatsuya Ashitani; Tetsuya Murayama; Koichi Ogiyama; Koetsu Takahashi |
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Publication Detail:
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Type: Journal Article Date: 2010-10-31 |
Journal Detail:
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Title: Journal of chemical ecology Volume: 36 ISSN: 1573-1561 ISO Abbreviation: J. Chem. Ecol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505563 Medline TA: J Chem Ecol Country: United States |
Other Details:
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Languages: eng Pagination: 1381-6 Citation Subset: IM |
Affiliation:
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The United Graduate School of Agricultural Science, Iwate University, 18-8 Ueda 3-chome, Morioka, Iwate, Japan. nori1005@tds1.tr.yamagata-u.ac.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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