Document Detail

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14.
MedLine Citation:
PMID:  14660414     Owner:  NLM     Status:  MEDLINE    
We report the identification and chemical characterization of four antifungal substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 micrograms ml-1.
Jörgen Sjögren; Jesper Magnusson; Anders Broberg; Johan Schnürer; Lennart Kenne
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  69     ISSN:  0099-2240     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-08     Completed Date:  2004-04-16     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7554-7     Citation Subset:  IM    
Department of Chemistry, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden.
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MeSH Terms
Antifungal Agents / pharmacology*
Culture Media, Conditioned
Decanoic Acids / chemistry,  pharmacology*
Fungi / drug effects*
Lactobacillus / genetics,  growth & development,  isolation & purification,  metabolism*
Microbial Sensitivity Tests
Molecular Sequence Data
Oleaceae / microbiology
Sequence Analysis, DNA
Reg. No./Substance:
0/Antifungal Agents; 0/Culture Media, Conditioned; 0/Decanoic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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