Document Detail


Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum.
MedLine Citation:
PMID:  23083817     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In continuation of our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of Calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model. The calophyllic acid (1A) and isocalophyllic acid (1B) mixture, canophyllic acid (4) and amentoflavone (5) showed dose dependent lipid lowering activity in in vivo experiments. The compounds 1A+1B mixture and 3 also showed good in vitro antioxidant activity.
Authors:
Janki Prasad; Atul Shrivastava; A K Khanna; G Bhatia; S K Awasthi; T Narender
Related Documents :
24507367 - Thermal and mechanical properties of fatty acid starch esters.
124557 - Sebum: analysis by infrared spectroscopy. ii. the suppression of fatty acids by systemi...
23025997 - Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor ...
24698377 - Nutrition: rejection is the fly's protection.
21605107 - Fractional filling with the microdepot technique as an alternative to bolus hyaluronic ...
15581847 - Reconstitution into liposomes of the glutamine/amino acid transporter from renal cell p...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-16
Journal Detail:
Title:  Phytomedicine : international journal of phytotherapy and phytopharmacology     Volume:  -     ISSN:  1618-095X     ISO Abbreviation:  Phytomedicine     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9438794     Medline TA:  Phytomedicine     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier GmbH. All rights reserved.
Affiliation:
Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226 001, U.P., India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid ...
Next Document:  Why should infectious disease physicians care for the hepatitis C-infected patient?