| Antidiabetic Effect of the Total Polyphenolic Acids Fraction from Salvia miltiorrhiza Bunge in Diabetic Rats. | |
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MedLine Citation:
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PMID: 22095927 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An investigation was made to evaluate the therapeutic potential of the total polyphenolic acids fraction (PAF) from Salvia miltiorrhiza Bunge in the type 2 diabetes mellitus rats model with an oral dose of 187 mg/kg for 28 days. The results showed that PAF induced a significant decrease in fasting blood glucose (FBG), fasting blood insulin (FINS), total cholesterol (TC), triglyceride (TG) and blood urea nitrogen (BUN), and an obvious increase in insulin sensitivity index (ISI) in diabetic rats induced by a high fat diet and a low dose of streptozocin (STZ). These results suggested that PAF has antidiabetic potential in vivo. Copyright © 2011 John Wiley & Sons, Ltd. |
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Authors:
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Mingqing Huang; Youliang Xie; Lidian Chen; Kedan Chu; Shuisheng Wu; Jinjian Lu; Xiuping Chen; Yitao Wang; Xiaoping Lai |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-17 |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: - ISSN: 1099-1573 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 John Wiley & Sons, Ltd. |
Affiliation:
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College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian Province, 350108, China; State Key Laboratory of Quality Research in Chinese Medicine, Macau, 999078, China; Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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