Document Detail

Antidepressants in clinical practice: limitations of assessment methods and drug response.
MedLine Citation:
PMID:  12404605     Owner:  NLM     Status:  Publisher    
There is a recognized gap between knowledge derived from 'efficacy' data - based on usually brief randomized controlled trials and findings in natural practice 'effectiveness' studies. In considering the limitations of current antidepressants in clinical practice, we have selected three clinically important issues to examine in a natural practice data base that has been in existence for several years. These relate to: (1) Diagnostic heterogeneity and potential advances using functional brain imaging; (2) Variability of outcome measures during treatment and (3) Time to response and prediction of outcome. Copyright 2001 John Wiley & Sons, Ltd.
Sidney H Kennedy; Beata S Eisfeld; Jeffrey H Meyer; R Michael Bagby
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Publication Detail:
Journal Detail:
Title:  Human psychopharmacology     Volume:  16     ISSN:  1099-1077     ISO Abbreviation:  Hum Psychopharmacol     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2002-Oct-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8702539     Medline TA:  Hum Psychopharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  105-114     Citation Subset:  -    
Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.
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