Document Detail

Anticonvulsants during electroconvulsive therapy: review and recommendations.
MedLine Citation:
PMID:  17548985     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To review the literature on the concurrent use of electroconvulsive therapy (ECT) and anticonvulsant drugs (AC) and to provide recommendations to guide clinical practice. METHODS: A MEDLINE search (1985-2006) was performed, using the terms "electroconvulsive therapy," "anticonvulsants," "epilepsy," "carbamazepine," "gabapentin," "lamotrigine," "topiramate," and "valproate," supplemented by manual searches of guidelines and textbooks on ECT. RESULTS: To date, no prospective, randomized and controlled trials examining outcome and safety of the AC-ECT combination have been published. Existing data are from case reports on the use of ECT for psychiatric conditions that are simultaneously treated with AC, and from case reports of patients treated with ECT and AC for epilepsy or for psychiatric conditions with comorbid epilepsy. Apart from an occasional difficulty in eliciting seizures, no severe adverse effects or complications are reported. CONCLUSIONS: The literature that is currently available indicates that ECT can be safely and effectively administered to patients treated with various AC. There is, however, no evidence to combine the 2 treatment modalities to augment therapeutic efficacy.
Pascal Sienaert; Joseph Peuskens
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The journal of ECT     Volume:  23     ISSN:  1095-0680     ISO Abbreviation:  J ECT     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-05     Completed Date:  2007-08-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808943     Medline TA:  J ECT     Country:  United States    
Other Details:
Languages:  eng     Pagination:  120-3     Citation Subset:  IM    
Electroconvulsive Therapy Department and Department of Mood Disorders, University Psychiatric Center-Katholieke Universiteit Leuven, Campus Kortenberg, Leuvensesteenweg, Kortenberg, Belgium.
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MeSH Terms
Anticonvulsants / administration & dosage*
Electroconvulsive Therapy*
Epilepsy / drug therapy
Reg. No./Substance:

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