| Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens. | |
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MedLine Citation:
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PMID: 20499099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We propose maslinic acid (2-alpha, 3-beta-dihydroxiolean-12-en-28-oic acid), found in the leaves and fruit of the olive tree (Olea europaea L.), as a new natural coccidiostatic product against Eimeria tenella. Its action in infected animals has been compared with animals treated with sodium salinomycin. The lesion index (LS), the oocyst index (OI) and the anticoccidial index (ACI) were studied with regard to the weight of the chicks. The ACI for maslinic acid was 210.27 and for sodium salinomycin 173.09. Similarly, both LS and OI decreased in the groups treated with maslinic acid. A considerable increase in weight was found in the chicks treated with maslinic acid compared with those in the control group. Histopathological studies of the caecum at 120 h post-infection showed that the infection rate decreased significantly in chicks treated with maslinic acid. |
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Authors:
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Luis Miguel De Pablos; Maria Fatima Brazil dos Santos; Enrique Montero; Andrés Garcia-Granados; Andrés Parra; Antonio Osuna |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-25 |
Journal Detail:
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Title: Parasitology research Volume: 107 ISSN: 1432-1955 ISO Abbreviation: Parasitol. Res. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-11-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703571 Medline TA: Parasitol Res Country: Germany |
Other Details:
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Languages: eng Pagination: 601-4 Citation Subset: IM |
Affiliation:
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Instituto de Biotecnología, Grupo de Bioquímica y Parasitología Molecular, Campus de Fuentenueva, Edif. Mecenas, Universidad de Granada, Granada, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cecum / parasitology, pathology Chickens Coccidiosis / drug therapy, pathology, veterinary* Coccidiostats / administration & dosage, therapeutic use* Eimeria tenella / drug effects* Olea / chemistry Poultry Diseases / drug therapy*, parasitology, pathology Pyrans / administration & dosage, therapeutic use Treatment Outcome Triterpenes / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Coccidiostats; 0/Pyrans; 0/Triterpenes; 4373-41-5/maslinic acid; 53003-10-4/salinomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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