Document Detail

Anticoagulation in atrial fibrillation: the trials and tribulations of keeping within therapeutic range.
MedLine Citation:
PMID:  18402716     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation (AF) is a growing epidemic in the developed world that has attracted much attention due to the associated risk of stroke and thromboembolism. This article discusses the application of oral anticoagulation (OAC) therapy with vitamin K antagonists (VKA) in order to reduce these risks. The article provides an overview of OAC management and highlights the need for greater efforts to increase time within therapeutic range.
Jaspal S Taggar; Gregory Y H Lip
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Publication Detail:
Type:  Editorial     Date:  2008-04-09
Journal Detail:
Title:  Current medical research and opinion     Volume:  24     ISSN:  1473-4877     ISO Abbreviation:  Curr Med Res Opin     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-16     Completed Date:  2008-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0351014     Medline TA:  Curr Med Res Opin     Country:  England    
Other Details:
Languages:  eng     Pagination:  1455-8     Citation Subset:  IM    
University Department of Medicine, City Hospital, Birmingham, UK.
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MeSH Terms
Administration, Oral
Aged, 80 and over
Anticoagulants / administration & dosage*,  adverse effects
Atrial Fibrillation / complications,  drug therapy*,  mortality*
Dose-Response Relationship, Drug
Drug Administration Schedule
Great Britain
Maximum Tolerated Dose
Randomized Controlled Trials as Topic
Risk Assessment
Severity of Illness Index
Stroke / prevention & control*
Survival Analysis
Treatment Outcome
Reg. No./Substance:

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