Document Detail

Anticoagulation for atrial fibrillation: should warfarin be temporarily stopped or continued after acute cardioembolic stroke?
MedLine Citation:
PMID:  20858671     Owner:  NLM     Status:  MEDLINE    
Despite anticoagulation for atrial fibrillation, some patients still suffer an ischaemic stroke. The issue of whether to stop or continue warfarin, or possibly to reverse the anticoagulation is an area of uncertainty. Continued anticoagulation may, however, increase haemorrhagic transformation of the infarct. In this article we review the published evidence in an attempt to quantify the risks and benefits of each treatment strategy and identify areas for further research.
Paul D Mudd; Martin A James
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-09-21
Journal Detail:
Title:  Age and ageing     Volume:  39     ISSN:  1468-2834     ISO Abbreviation:  Age Ageing     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  2011-01-31     Revised Date:  2011-09-23    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  England    
Other Details:
Languages:  eng     Pagination:  670-3     Citation Subset:  IM    
Department of Stroke Medicine, Royal Devon and Exeter Hospital, Exeter, Devon, UK.
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MeSH Terms
Acute Disease
Anticoagulants / administration & dosage*
Atrial Fibrillation / drug therapy*,  epidemiology*
Evidence-Based Medicine
Intracranial Embolism / epidemiology*
Practice Guidelines as Topic
Risk Factors
Stroke / epidemiology*
Warfarin / administration & dosage*
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin
Comment In:
Age Ageing. 2011 Sep;40(5):647; author reply 647   [PMID:  21835935 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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