Document Detail

MedLine Citation:
PMID:  11092099     Owner:  NLM     Status:  MEDLINE    
Anticoagulation is a treatment with significant and life threatening complications requiring that the balance of risk and benefit be individually assessed in each patient. The risks are greater in the elderly and those with hypertension, falls and gastrointestinal disease. The use of anticoagulants is now established in patients with symptomatic non-rheumatic atrial fibrillation, especially older patients with hypertension, cardiac failure or a large left atrium or left ventricular dysfunction. There is, however, no place for the routine use of anticoagulants in acute stroke or as part of secondary prevention in patients in sinus rhythm. There may be a place, though as yet the evidence would not support this, for the limited use of anticoagulants in special situations such as cortical venous thrombosis or carotid dissection.
G S Venables
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British medical bulletin     Volume:  56     ISSN:  0007-1420     ISO Abbreviation:  Br. Med. Bull.     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-08     Completed Date:  2000-12-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376542     Medline TA:  Br Med Bull     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  501-9     Citation Subset:  IM    
Department of Neurology, Central Sheffield University Hospitals NHS Trust, UK.
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MeSH Terms
Anticoagulants / adverse effects,  therapeutic use*
Atrial Fibrillation / prevention & control
Risk Assessment
Sinus Thrombosis, Intracranial / drug therapy
Stroke / prevention & control*
Reg. No./Substance:

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