Document Detail

Anticoagulants, aspirin and dipyridamole in the secondary prevention of cerebral ischaemia: which is the best for which patient?
MedLine Citation:
PMID:  17971645     Owner:  NLM     Status:  MEDLINE    
In this paper, an overview is given of trials with oral anticoagulants and dipyridamole in the secondary prevention after transient ischaemic attack or minor stroke. In patients with atrial fibrillation, the secondary preventive treatment of first choice is oral anticoagulation with an aimed international normalised ratio between 2.0 and 3.0. In patients without a cardiac source of embolism, a combination therapy of low-dose aspirin and dipyridamole 200 mg twice daily is the treatment of choice. These treatment strategies do however not prevent all recurrent strokes or vascular complications, and research for more effective strategies is warranted.
P H A Halkes; A Algra
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-11-01
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  24 Suppl 1     ISSN:  1015-9770     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:  2007  
Date Detail:
Created Date:  2007-10-31     Completed Date:  2008-01-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  107-11     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
Department of Neurology, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.
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MeSH Terms
Anticoagulants / therapeutic use*
Aspirin / therapeutic use*
Brain Ischemia / prevention & control*
Dipyridamole / therapeutic use*
Platelet Aggregation Inhibitors / therapeutic use*
Stroke / prevention & control
Reg. No./Substance:
0/Anticoagulants; 0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin; 58-32-2/Dipyridamole

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