Document Detail


Anticoagulant Therapy for Venous Thromboembolism during Pregnancy - Implications for Neuraxial Analgesia/Anesthesia.
MedLine Citation:
PMID:  23332082     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We read Romualdi et al's recent systematic review and meta-analysis of anticoagulant therapy for venous thromboembolism (VTE) during pregnancy (1) with great interest. They conclude that anticoagulant therapy (primarily low molecular weight heparin [LMWH] in > 80% of cases) is safe and effective with a low incidence of antenatal (1.41% weighted mean incidence [WMI]) and early postnatal (1.9% WMI) major bleeding. While this data is reassuring, as anesthesiologists we are both curious and concerned about the implications for safe provision of neuraxial (primarily epidural) labor analgesia and/or anesthesia for parturients receiving LMWH. © 2013 International Society on Thrombosis and Haemostasis.
Authors:
Madhumani Rupasinghe; Timothy C Hollenbeck; Sara Guzman-Reyes; Manjunath M Shetty; Anita Giezentanner; Davide Cattano; Evan G Pivalizza
Publication Detail:
Type:  LETTER     Date:  2013-1-18
Journal Detail:
Title:  Journal of thrombosis and haemostasis : JTH     Volume:  -     ISSN:  1538-7836     ISO Abbreviation:  J. Thromb. Haemost.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101170508     Medline TA:  J Thromb Haemost     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 International Society on Thrombosis and Haemostasis.
Affiliation:
University of Texas Medical School, Houston.
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