| Anticardiolipin antibodies are no marker for survived myocardial infarction. | |
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MedLine Citation:
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PMID: 2376955 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antiphospholipid antibodies--both the lupus anticoagulant and anticardiolipin antibodies--are closely associated with arterial and venous thrombosis. In this prospective trial the IgM- and IgG-anticardiolipin antibodies in serum were determined in acute and chronic coronary artery disease. Seventy-four unselected males (34-87 years, mean 60) were included in the study. All patients underwent coronary angiography; infectious and autoimmune diseases were exclusion criteria. Sixteen patients had coronary artery disease (group A), 34 showed coronary stenoses with prior infarction (B), and 14 had survived an acute myocardial infarction (C), whereas 10 patients revealed no significant coronary narrowing (D; controls). The major risk factors were the same for all groups. Neither the IgM- nor the IgG-anticardiolipin antibody levels showed any significant difference in the four groups. The severity of coronary artery disease did not correlate to these antibodies. Furthermore, no correlation was found between elevated anticardiolipin antibodies and thrombocyte levels. Thus, a higher anticardiolipin level does not appear to be a marker for recurrent cardiovascular events. |
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Authors:
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B Eber; E Kronberger-Schaffer; H Brussee; G Klima; A Obernosterer; M Toporsch; J Dusleag; W Klein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Klinische Wochenschrift Volume: 68 ISSN: 0023-2173 ISO Abbreviation: Klin. Wochenschr. Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-09-05 Completed Date: 1990-09-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985205R Medline TA: Klin Wochenschr Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 594-6 Citation Subset: IM |
Affiliation:
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Medizinische Universitätsklinik Graz, Kardiologie, Osterreich. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Autoantibodies / analysis* Cardiolipins / immunology* Coronary Disease / diagnosis*, immunology Follow-Up Studies Humans Immunoglobulin G / analysis Immunoglobulin M / analysis Male Middle Aged Myocardial Infarction / diagnosis*, immunology, mortality Prospective Studies Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Cardiolipins; 0/Immunoglobulin G; 0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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