Document Detail


Anticarcinogenic actions of water-soluble and alcohol-insoluble fractions from culture medium of Lentinus edodes mycelia.
MedLine Citation:
PMID:  6891904     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The water-soluble (LEM) and alcohol-insoluble (LAP and LAP1) fractions were prepared from the culture medium of Lentinus edodes mycelia which was composed of bagasse and rice bran. LEM suppressed rat hepatocarcinogenesis and its cell proliferation of rat-ascites hepatoma to about 50% or less of each control group. LAP also suppressed cell proliferation at almost the same rate. LAP1 induced many small cells in the ascites and significantly raised the survival rate of hepatoma-bearing rats. Thus, anticarcinogenic action was revealed in LAP or LAP1 fractions which were mainly composed of xylose-containing polysaccharide and protein.
Authors:
N Sugano; Y Hibino; Y Choji; H Maeda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer letters     Volume:  17     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:    1982 Nov-Dec
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  109-14     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Agaricales / analysis*
Animals
Antineoplastic Agents*
Cell Division / drug effects
Liver Neoplasms, Experimental / drug therapy*,  physiopathology
Male
Plant Extracts / therapeutic use*
Rats
Rats, Inbred Strains
Solubility
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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