Document Detail


Anticancer activity of Carica papaya: A review.
MedLine Citation:
PMID:  23212988     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Carica papaya is widely cultivated in tropical and subtropical countries and is used as food as well as traditional medicine to treat a range of diseases. Increasing anecdotal reports of its effects in cancer treatment and prevention, with many successful cases, have warranted that these pharmacological properties be scientifically validated. A bibliographic search was conducted using the key words "papaya", "anticancer", and "antitumor" along with cross-referencing. No clinical or animal cancer studies were identified and only seven in vitro cell-culture-based studies were reported; these indicate that C. papaya extracts may alter the growth of several types of cancer cell lines. However, many studies focused on specific compounds in papaya and reported bioactivity including anticancer effects. This review summarizes the results of extract-based or specific compound-based investigations and emphasizes the aspects that warrant future research to explore the bioactives in C. papaya for their anticancer activities.
Authors:
Thao T T Nguyen; Paul N Shaw; Marie-Odile Parat; Amitha K Hewavitharana
Related Documents :
24653608 - Alterations of plasma lipid profile patterns in oral leukoplakia.
20232198 - Bacteriophages and cancer.
24463158 - Fruit-derived phenolic compounds and pancreatic cancer: perspectives from australian na...
16153858 - Toll-like receptors, inflammation and cancer.
24586838 - Association between socioeconomic factors and cancer risk: a population cohort study in...
12509768 - Screening for lung cancer: in pursuit of pre-metastatic disease.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-5
Journal Detail:
Title:  Molecular nutrition & food research     Volume:  -     ISSN:  1613-4133     ISO Abbreviation:  Mol Nutr Food Res     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231818     Medline TA:  Mol Nutr Food Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
School of Pharmacy,, The University of Queensland, Brisbane, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of BMP4/SMAD signaling pathway on mouse primordial follicle growth and survival via up-regul...
Next Document:  Bioengineered chimeric spider silk-uranium binding proteins.