| Antibody dependent and spontaneous lymphocyte mediated cytotoxicity in normal subjects, patients with SLE, and malignancies. | |
| | |
MedLine Citation:
|
PMID: 617926 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Antibody dependent and spontaneous lymphocyte mediated cytotoxicity was studied in healthy subjects and patients with systemic lupus erythematosus and metastatic tumours. The purified peripheral blood lymphocytes of healthy subjects exerted a similar cytotoxic activity on allogeneic K-562 and xenogeneic chicken erythrocyte targets in the antibody dependent and spontaneous lymphocyte mediated cytotoxicity tests. There was a stronger correlation between the cytotoxicity measured in the two allogeneic assays than between allogeneic and xenogeneic tests. Allogeneic systems using K-562 targets were more sensitive to changes in cytotoxic activity in systemic lupus erythematosus and metastatic tumours than was the xenogeneic chicken erythrocyte assay. |
| | |
Authors:
|
I Láng; M Benczur; M Varga; P Gergely; G Petrányi |
Related Documents
:
|
2425456 - Functional analysis of the hla-a2/aw68 recombinant molecule hla-aw69: epstein-barr viru... 4599426 - Malignant melanoma: specific immunity induced by bacillus calmette-guérin in balb-c mice. 19377306 - A novel antibody fragment targeting hab18g/cd147 with cytotoxicity and decreased immuno... 2957436 - Induction of calcium flux and enhancement of cytolytic activity in natural killer cells... 6268546 - Inactivation of varicella zoster virus in vitro: effect of leukocytes and specific anti... 22305416 - Chronic pneumonia in calves after experimental infection with mycoplasma bovis strain 1... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta medica Academiae Scientiarum Hungaricae Volume: 34 ISSN: 0001-5989 ISO Abbreviation: Acta Med Acad Sci Hung Publication Date: 1977 |
Date Detail:
|
Created Date: 1979-04-28 Completed Date: 1979-04-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370323 Medline TA: Acta Med Acad Sci Hung Country: HUNGARY |
Other Details:
|
Languages: eng Pagination: 123-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antibody-Dependent Cell Cytotoxicity* Breast Neoplasms / immunology Humans Intestinal Neoplasms / immunology Lung Neoplasms / immunology Lupus Erythematosus, Systemic / immunology* Lymphocytes / immunology* Neoplasm Metastasis Neoplasms / immunology* Tongue Neoplasms / immunology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: In vitro effect of immune complex positive human sera on antibody dependent cellular cytotoxicity.
Next Document: A critical analysis of some thyroid function tests.