| Antibody-dependent cellular cytotoxicity of mononuclear cells from asthmatics tested in three in vitro assays. | |
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MedLine Citation:
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PMID: 355294 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using the chicken red blood cell assay, the human Chang liver cell assay, and a lymphoblastoid cell assay, mononuclear cells from asthmatics and normals were tested for antibody-dependent cellular cytotoxicity (ADCC) capacity. Mononuclear cell preparations from perennial nonallergic asthmatics with a history of asthma associated with viral infections had a reduced ADCC capacity in the chicken red blood cell assay, an increased ADCC capacity in the Chang liver cell assay, and normal ADCC capacity in the lymphoblastoid cell assay. The data also suggested that perennial nonallergic asthmatics had increased percentages of surface IgG-negative lymphocytes in the peripheral blood when compared to normals. |
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Authors:
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D K Flaherty; J M Martin; J E Surfus; J B Kooistra; C E Reed |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of allergy and clinical immunology Volume: 62 ISSN: 0091-6749 ISO Abbreviation: J. Allergy Clin. Immunol. Publication Date: 1978 Sep |
Date Detail:
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Created Date: 1978-10-27 Completed Date: 1978-10-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1275002 Medline TA: J Allergy Clin Immunol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 156-61 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Animals Antibody-Dependent Cell Cytotoxicity* Asthma / immunology* Chickens Erythrocytes / immunology Female Fluorescent Antibody Technique Humans Leukocyte Count Liver / immunology Male Middle Aged Phagocytes / immunology* Receptors, Antigen, B-Cell |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Antigen, B-Cell |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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