Document Detail


Antibody-dependent cellular cytotoxicity in asthmatics.
MedLine Citation:
PMID:  319137     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using a 51Cr-labeled, antibody-coated chicken red blood cell assay system, mononuclear cell and granulocyte preparations from infectious asthmatics, noinfectious asthmatics, and normal controls were tested for antibody-dependent cellular cytotoxicity (ADCC) capacity. The corrected cytotoxic indices of mononuclear cell preparations from infectious asthmatics were reduced (34 +/- 10 SD) as compared to noninfectious asthmatiics (47 +/- 7 SD) or normal controls (47 +/- 6 SD). Granulocyte preparations from infectious asthmatics and normal controls had a severity of the disease or in vivo drug treatment.
Authors:
D K Flaherty; J M Martin; W W Storms; R J Kris; J E Surfus; C E Reed
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  59     ISSN:  0091-6749     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-03-21     Completed Date:  1977-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  48-53     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibody Specificity*
Asthma / complications,  immunology*
Communicable Diseases / complications
Cytotoxicity Tests, Immunologic
Granulocytes / immunology
Humans
Immunity, Cellular*
Immunologic Techniques
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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