Document Detail

Antibodies to sporozoites: their frequent occurrence in individuals living in an area of hyperendemic malaria.
MedLine Citation:
PMID:  386511     Owner:  NLM     Status:  MEDLINE    
Serum samples from 158 West Africans were tested for antibodies against sporozoites, the vector stage of the malaria parasite. Antibodies specific for Plasmodium falciparum sporozoites were detected by means of the circumsporozoite precipitation assay and indirect immunofluorescence. More than 90 percent of the serum samples from adults gave positive immunofluorescent reactions against falciparum sporozoites, whereas most of the samples from children gave low or negative reactions.
E H Nardin; R S Nussenzweig; I A McGregor; J H Bryan
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  206     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2007-03-19    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  597-9     Citation Subset:  IM    
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MeSH Terms
Age Factors
Antibodies / analysis*
Child, Preschool
Disease Reservoirs / immunology
Fluorescent Antibody Technique
Malaria / immunology*
Middle Aged
Plasmodium falciparum / immunology*
Reg. No./Substance:
0/Antibodies; 0/Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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