| Antibodies to dehistonized chromatin of normal and fetal rat liver. | |
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MedLine Citation:
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PMID: 6199117 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antisera to dehistonized adult or fetal rat liver chromatin were treated with electrophoretically separated chromosomal proteins of adult and fetal liver, Novikoff hepatoma and adult rat kidney. Both types of antisera reacted with numerous antigens in both tissue chromatins. However, immunoabsorption experiments have shown that while adult rat liver shared most of its nuclear antigens with other tissues, antisera to dehistonized fetal liver chromatins were more specific. In terms of antigenic specificity, the fetal rat liver and Novikoff hepatoma chromatins were similar; however, the former contained several antigens which could not be absorbed with Novikoff hepatoma chromatin. |
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Authors:
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Z Kilianska; W N Schmidt; L S Hnilica |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Cell differentiation Volume: 13 ISSN: 0045-6039 ISO Abbreviation: Cell Differ. Publication Date: 1983 Nov |
Date Detail:
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Created Date: 1984-03-29 Completed Date: 1984-03-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0342640 Medline TA: Cell Differ Country: IRELAND |
Other Details:
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Languages: eng Pagination: 225-31 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies* Chromatin / immunology* Chromosomal Proteins, Non-Histone / immunology Epitopes Fetus / immunology Kidney / immunology Liver / immunology* Liver Neoplasms, Experimental / immunology Male Rats Rats, Inbred Strains |
| Grant Support | |
ID/Acronym/Agency:
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CA 26412/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Chromatin; 0/Chromosomal Proteins, Non-Histone; 0/Epitopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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