Document Detail


Antibiotics for Irritable Bowel Syndrome: Rationale and Current Evidence.
MedLine Citation:
PMID:  22945316     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Irritable bowel syndrome (IBS) is the most common gastrointestinal condition effecting adults in developed countries worldwide. Over the last decade, evidence has emerged suggesting that gut bacteria play a role in the pathophysiology of IBS. While difficult to identify using noninvasive means, one of the most common attributable bacterial concepts in IBS is the small intestinal bacterial overgrowth hypothesis (SIBO). In this article, we review the different mechanisms by which gut flora and, specifically, SIBO may contribute to IBS and the evidence supporting the use of various antibiotic therapies in treating IBS.
Authors:
Amit H Sachdev; Mark Pimentel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-4
Journal Detail:
Title:  Current gastroenterology reports     Volume:  -     ISSN:  1534-312X     ISO Abbreviation:  Curr Gastroenterol Rep     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888896     Medline TA:  Curr Gastroenterol Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
GI Motility Laboratory, Cedars-Sinai Medical Center, 8730 Alden Drive Thalians Building, 2nd floor East, Los Angeles, CA, 90048, USA.
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