Document Detail


Antibiotic therapy for arterial infection: lessons from the successful treatment of a mycotic femoral artery aneurysm without surgical reconstruction.
MedLine Citation:
PMID:  2261327     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A mycotic femoral artery aneurysm developed in a diabetic man with bacteremia from a Staphylococcus aureus urinary tract infection. Because of severe concomitant congestive heart failure and hypothyroidism, surgical reconstruction of the femoral artery was deferred while the patient received an intensive course of intravenous nafcillin. This led to stabilization of the size of the femoral aneurysm for two years, during which time it remained asymptomatic. Three such cases of nonsurgical treatment of a mycotic aneurysm have been documented. Surgical ligation, drainage, and bypass remain the mainstay therapies for mycotic aneurysms, but these cases demonstrate the possibility of sterilizing a primary arterial infection under the highly selected circumstances of an exquisitely sensitive organism, absence of periarterial abscess and readily observable anatomic location. Most importantly, these cases provide assurance that a six-week course of parenteral antibiotics is a reasonable adjunctive treatment for residual endovascular infection.
Authors:
J L Kaufman; R Smith; G C Capel; D M Shah; B B Chang; R P Leather
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of vascular surgery     Volume:  4     ISSN:  0890-5096     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-02-05     Completed Date:  1991-02-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-6     Citation Subset:  IM    
Affiliation:
Department of Surgery, Albany VAMC, New York 12208.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aneurysm, Infected / drug therapy*,  microbiology,  radiography
Femoral Artery / radiography
Humans
Male
Nafcillin / therapeutic use*
Staphylococcal Infections / drug therapy*
Staphylococcus aureus / isolation & purification
Chemical
Reg. No./Substance:
147-52-4/Nafcillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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