Document Detail

Antibiotic prophylaxis in neurosurgery. A randomized controlled trial.
MedLine Citation:
PMID:  6368765     Owner:  NLM     Status:  MEDLINE    
A randomized trial was performed to support the contention that prophylactic antibiotics can reduce the incidence of postoperative neurosurgical wound infections. The regime outlined by Malis was followed. Vancomycin and gentamicin were administered systemically just prior to surgery and streptomycin was added to the irrigating solution. Patients were randomly assigned to two groups: control and treated. The infection rate in the control group was 3.5% and in the treated group 0.5%.
J Geraghty; M Feely
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  60     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-05-02     Completed Date:  1984-05-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  724-6     Citation Subset:  AIM; IM    
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MeSH Terms
Anti-Bacterial Agents / therapeutic use*
Clinical Trials as Topic
Gentamicins / therapeutic use
Middle Aged
Random Allocation
Streptomycin / therapeutic use
Surgical Wound Infection / prevention & control*
Vancomycin / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Gentamicins; 1404-90-6/Vancomycin; 57-92-1/Streptomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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