Document Detail

Antibiotic lock for treatment of tunneled hemodialysis catheter bacteremia.
MedLine Citation:
PMID:  19000121     Owner:  NLM     Status:  MEDLINE    
Catheter-related bacteremia is a major cause of morbidity and mortality among catheter-dependent hemodialysis patients. Microorganism biofilm matrix formation in the catheter is the pathogenic process of this entity. Administration of systemic antibiotics and removal of the offending catheter is the most logical treatment. This article discusses an alternative option, instillation of an antibiotic-lock solution into the lumen of the catheter plus systemic antibiotic therapy. Recent studies suggest that this strategy could treat the infection and salvage the catheter, thus avoiding the need for further interventional procedures including but not limited to the removal of the catheter, placement of a temporary catheter, and finally placement of a new permanent catheter. The implementation of this effective approach will reduce morbidity and possibly reduce the cost and interventions associated with it.
Ivan D Maya
Publication Detail:
Type:  Journal Article     Date:  2008-09-24
Journal Detail:
Title:  Seminars in dialysis     Volume:  21     ISSN:  1525-139X     ISO Abbreviation:  Semin Dial     Publication Date:    2008 Nov-Dec
Date Detail:
Created Date:  2008-12-10     Completed Date:  2009-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  United States    
Other Details:
Languages:  eng     Pagination:  539-41     Citation Subset:  IM    
Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.
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MeSH Terms
Anti-Bacterial Agents / administration & dosage*
Bacteremia / drug therapy*
Catheter-Related Infections / drug therapy*
Catheterization / adverse effects*,  instrumentation*
Equipment Design
Renal Dialysis / instrumentation*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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