Document Detail


Antibiotic use in premature infants after discharge from the neonatal intensive care unit.
MedLine Citation:
PMID:  19448131     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using a retrospective cohort of premature infants, we constructed multivariable Poisson models to determine factors associated with the receipt of antibiotics during the first year after discharge, N = 891. Black race (incidence rate ratio 1.80 compared with White infants, P = .008), male gender (incidence rate ratio 1.44; P = .007), bronchopulmonary dysplasia (incidence rate ratio 1.47; P = .04), and each additional child at home (incidence rate ratio 1.21, P = .002) increased the receipt of antibiotics for any reason. Male gender and additional children at home increased the receipt of non-recommended antibiotics, while Black infants received care at facilities that prescribed more non-recommended antibiotics. Even in a high-risk population of children, factors other than the medical history and presentation of the child may alter antibiotic prescription patterns and result in variations in care.
Authors:
Scott A Lorch; Kelly C Wade; Susan Bakewell-Sachs; Barbara Medoff-Cooper; Jeffrey H Silber; Gabriel J Escobar
Publication Detail:
Type:  Journal Article     Date:  2009-05-15
Journal Detail:
Title:  Clinical pediatrics     Volume:  49     ISSN:  1938-2707     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-18     Completed Date:  2010-05-19     Revised Date:  2011-08-25    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  249-57     Citation Subset:  AIM; IM    
Affiliation:
Center for Outcomes Research, The Children's Hospital of Philadelphia, 3535 Market Street, Philadelphia, PA 19104, USA. lorch@email.chop.edu
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MeSH Terms
Descriptor/Qualifier:
African Americans / statistics & numerical data*
Anti-Bacterial Agents / administration & dosage*
Bronchopulmonary Dysplasia / drug therapy
Drug Utilization Review
European Continental Ancestry Group / statistics & numerical data*
Female
Humans
Incidence
Infant
Infant, Newborn
Infant, Premature*
Intensive Care Units, Neonatal*
Male
Multivariate Analysis
Patient Discharge*
Poisson Distribution
Retrospective Studies
Sex Factors
Time Factors
United States
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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