Document Detail


Antibiofilm polysaccharides.
MedLine Citation:
PMID:  22730907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bacterial extracellular polysaccharides have been shown to mediate many of the cell-to-cell and cell-to-surface interactions that are required for the formation, cohesion and stabilization of bacterial biofilms. However, recent studies have identified several bacterial polysaccharides that inhibit biofilm formation by a wide spectrum of bacteria and fungi both in vitro and in vivo. This review discusses the composition, modes of action and potential biological roles of antibiofilm polysaccharides recently identified in bacteria and eukarya. Some of these molecules may have technological applications as antibiofilm agents in industry and medicine.
Authors:
Olaya Rendueles; Jeffrey B Kaplan; Jean-Marc Ghigo
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2012-06-26
Journal Detail:
Title:  Environmental microbiology     Volume:  15     ISSN:  1462-2920     ISO Abbreviation:  Environ. Microbiol.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-29     Completed Date:  2013-09-23     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  100883692     Medline TA:  Environ Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  334-46     Citation Subset:  IM    
Copyright Information:
© 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.
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MeSH Terms
Descriptor/Qualifier:
Bacteria / chemistry,  metabolism
Biofilms*
Lipopolysaccharides / metabolism
Polysaccharides, Bacterial / physiology*
Grant Support
ID/Acronym/Agency:
AI82392/AI/NIAID NIH HHS; HHSN261200800001E/CA/NCI NIH HHS; R21 AI082392/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Lipopolysaccharides; 0/Polysaccharides, Bacterial
Comments/Corrections

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