Document Detail

Antibacterial properties of soap containing some fatty acid esters.
MedLine Citation:
PMID:  19460009     Owner:  NLM     Status:  In-Data-Review    
Synopsis Chemical microbial inhibitors compatible with formulations of soaps and deodorant perfumes are more effective if they are substantive to the skin. However, highly effective inhibitors are toxic and their substantivity on skin may accentuate the toxicity. Natural compounds such as short to medium chain fatty acids and their derivatives, which are known to be germicidal, offer a viable alternative to chemical inhibitors. We report here the synthesis of sodium 2-lauroyloxy propionate and an in vivo method to test its substantivity on skin following its incorporation in soaps. Among several compounds tested, sodium 2-lauroyloxy propionate was found to be highly substantive in soap formulation.
N K Pandey; C V Natraj; G P Kalle; M E Nambudiry
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cosmetic science     Volume:  7     ISSN:  0142-5463     ISO Abbreviation:  Int J Cosmet Sci     Publication Date:  1985 Feb 
Date Detail:
Created Date:  2009-05-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007161     Medline TA:  Int J Cosmet Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  9-14     Citation Subset:  -    
Hindustan Lever Research Centre, Andheri (East), Bombay 400 099, India.
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