| Antibacterial properties of the skin mucus of the freshwater fishes, Rita rita and Channa punctatus. | |
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MedLine Citation:
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PMID: 21780547 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVES: The skin mucus of Rita rita and Channa punctatus was investigated to explore the possibilities of its antibacterial properties. MATERIALS AND METHODS: Skin mucus was extracted in acidic solvents (0.1% trifluoroacetic acid and 3% acetic acid) and in triple distilled water (aqueous medium). The antibacterial activity of the mucus extracts was analyzed, using disc diffusion method, against five strains of bacteria--the Gram-positive Staphylococcus aureus and Micrococcus luteus; and the Gram negative Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi. RESULTS: In both Rita rita and Channa punctatus, the skin mucus extracted in acidic solvents as well as in aqueous medium show antibacterial activity against Staphylococcus aureus and Micrococcus luteus. Nevertheless, the activity is higher in acidic solvents than that in aqueous medium. The acidic mucus extracts of Rita rita, show antibacterial activity against Salmonella typhi as well. CONCLUSIONS: The results suggest that fish skin mucus have bactericidal properties and thus play important role in the protection of fish against the invasion of pathogens. Fish skin mucus could thus be regarded as a potential source of novel antibacterial components. |
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Authors:
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U Kumari; A K Nigam; S Mitial; A K Mitial |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European review for medical and pharmacological sciences Volume: 15 ISSN: 1128-3602 ISO Abbreviation: Eur Rev Med Pharmacol Sci Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-07-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9717360 Medline TA: Eur Rev Med Pharmacol Sci Country: Italy |
Other Details:
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Languages: eng Pagination: 781-6 Citation Subset: IM |
Affiliation:
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Skin Physiology Laboratory, Centre of Advanced Study, Department of Zoology, Banaras Hindu University, Varanasi, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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