Document Detail


Antibacterial effect of garlic and omeprazole on Helicobacter pylori.
MedLine Citation:
PMID:  10404325     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The antibacterial effect of a home-made raw garlic extract and commercial garlic tablets alone and in combination with antibiotics or omeprazole was determined against clinical isolates of Helicobacter pylori. MIC values of raw garlic extract and three types of commercial garlic tablets ranged from 10,000 to 17,500 mg/L. When MIC values of the commercial tablets were based on the allicin content, no differences between the three types were observed. The combination of garlic and omeprazole, studied with killing curves, showed a synergic effect which was concentration dependent. Further clinical evaluation of garlic in combination with the conventional agents for H. pylori treatment seems warranted.
Authors:
D Jonkers; E van den Broek; I van Dooren; C Thijs; E Dorant; G Hageman; E Stobberingh
Related Documents :
16028975 - Preclinical evaluation of rapeseed, raspberry, and pine bark phenolics for health relat...
22566335 - Eating behavior and nutritional status in patients who underwent coronary angioplasty.
22874795 - Patients' evaluation of hospital foodservice quality in italy: what do patients really ...
3436895 - Enzyme-linked immunosorbent assay of benomyl and thiabendazole in some foods.
14647225 - Food insecurity is associated with dietary intake and body size of korean children from...
20972285 - Locally made ready to use therapeutic food for treatment of malnutrition a randomized c...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  43     ISSN:  0305-7453     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-09-30     Completed Date:  1999-09-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  837-9     Citation Subset:  IM    
Affiliation:
Department of Medical Microbiology, University Hospital Maastricht, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology
Anti-Ulcer Agents / pharmacology*
Drug Synergism
Garlic / chemistry*
Helicobacter pylori / drug effects*,  isolation & purification
Humans
Microbial Sensitivity Tests
Omeprazole / pharmacology*
Plant Extracts / pharmacology
Plants, Medicinal*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Ulcer Agents; 0/Plant Extracts; 73590-58-6/Omeprazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparative in-vitro activity of moxifloxacin, penicillin, ceftriaxone and ciprofloxacin against pne...
Next Document:  Factors associated with trimethoprim-resistant bacteria isolated from urine samples.