| Antibacterial effect of the bioactive compound beauvericin produced by Fusarium proliferatum on solid medium of wheat. | |
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MedLine Citation:
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PMID: 20371252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To obtain the bioactive compound beauvericin (BEA), Fusarium proliferatum CECT 20569 was grown on a solid medium of wheat, utilizing the technique of the solid state fermentation (SSF), being this mycotoxin purified by high performance liquid chromatography (HPLC) with a reverse phase semi-preparative column using as the mobile phase acetonitrile/water in gradient condition. The purity of the BEA was verified by analytical HPLC and liquid chromatography tandem mass spectrometry (LC/MS-MS). The pure fractions of BEA were utilized to determinate the antibiotic effects on several bacterial strains that are considered normally pathogens of the intestinal tract as: Escherichia coli, Enterococcus faecium, Salmonella enterica, Shigella dysenteriae, Listeria monocytogenes, Yersinia enterocolitica, Clostridium perfringens, Pseudomonas aeruginosa and Staphylococcus aureus. |
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Authors:
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G Meca; I Sospedra; J M Soriano; A Ritieni; A Moretti; J Mañes |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-03 |
Journal Detail:
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Title: Toxicon : official journal of the International Society on Toxinology Volume: 56 ISSN: 1879-3150 ISO Abbreviation: Toxicon Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-07-12 Completed Date: 2010-12-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1307333 Medline TA: Toxicon Country: England |
Other Details:
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Languages: eng Pagination: 349-54 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain. giuseppe.meca@uv.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology* Chromatography, Liquid Depsipeptides / pharmacology* Fusarium / metabolism* Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Ultraviolet Tandem Mass Spectrometry Triticum / metabolism*, microbiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Depsipeptides; 26048-05-5/beauvericin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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