Document Detail

Antibacterial activity of some bryophytes used traditionally for the treatment of burn infections.
MedLine Citation:
PMID:  21391844     Owner:  NLM     Status:  MEDLINE    
CONTEXT: Plagiochasma appendiculatum L. & L. (Aytoniaceae), Conocephalum conicum (L.) Necker (Conocephalaceae), Bryum argenteum Hedw. (Bryaceae), and Mnium marginatum (With.) P. Beauv. (Mniaceae) are bryophytes (liverworts and mosses) used by traditional healers for the treatment of burn, cuts, wounds, and skin disorders.
OBJECTIVE: This study evaluated the antibacterial activity of four bryophytes against some common bacteria responsible for burn infections.
MATERIALS AND METHODS: Different fractions of bryophytes were screened using the disc diffusion (qualitative) and broth microdilution (quantitative) methods, according to the guidelines of the National Committee for Clinical and Laboratory Standards.
RESULTS AND DISCUSSION: Chloroform fractions of liverworts were more active against Gram negative strains while butanol fractions of mosses had significant activity against Gram positive bacteria. Staphylococcus aureus was the most sensitive strain of those tested with the butanol fraction of M. marginatum (moss), with the strongest inhibition zone of 102.92% and minimum inhibitory concentration of 30 μg mL(-1).
CONCLUSION: Our findings support the use of the bryophytes in traditional medicine for burn infections because of their significant antibacterial activity.
Meenakshi Singh; Shweta Singh; Virendra Nath; Vinay Sahu; Ajay Kumar Singh Rawat
Related Documents :
22416054 - Efficacy of telavancin in patients with specific types of complicated skin and skin str...
21403784 - Infection with mycoplasma pneumoniae is not related to asthma control, asthma severity,...
22314524 - Canvas 1 and 2: analysis of clinical response at day 3 in two phase 3 trials of ceftaro...
23351654 - Imported diphyllobothriasis in switzerland: molecular methods to define a clinical case...
14762514 - Angiostrongylus costaricensis and experimental infection of sarasinula marginata ii: el...
22337824 - The dilemma of assessment bias in infection control research.
Publication Detail:
Type:  Journal Article     Date:  2011-03-11
Journal Detail:
Title:  Pharmaceutical biology     Volume:  49     ISSN:  1744-5116     ISO Abbreviation:  Pharm Biol     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-19     Completed Date:  2011-08-18     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  9812552     Medline TA:  Pharm Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  526-30     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anti-Bacterial Agents / pharmacology*
Bacterial Infections / drug therapy*
Burns / complications,  drug therapy*
Microbial Sensitivity Tests
Plant Extracts / pharmacology*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Specific pathogen-free status alters immunophenotype in rhesus macaques: implications for the study ...
Next Document:  Interview: The story of Advanced BioHealing: commercializing bioengineered tissue products.