Document Detail


Antibacterial activity of some bryophytes used traditionally for the treatment of burn infections.
MedLine Citation:
PMID:  21391844     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONTEXT: Plagiochasma appendiculatum L. & L. (Aytoniaceae), Conocephalum conicum (L.) Necker (Conocephalaceae), Bryum argenteum Hedw. (Bryaceae), and Mnium marginatum (With.) P. Beauv. (Mniaceae) are bryophytes (liverworts and mosses) used by traditional healers for the treatment of burn, cuts, wounds, and skin disorders.
OBJECTIVE: This study evaluated the antibacterial activity of four bryophytes against some common bacteria responsible for burn infections.
MATERIALS AND METHODS: Different fractions of bryophytes were screened using the disc diffusion (qualitative) and broth microdilution (quantitative) methods, according to the guidelines of the National Committee for Clinical and Laboratory Standards.
RESULTS AND DISCUSSION: Chloroform fractions of liverworts were more active against Gram negative strains while butanol fractions of mosses had significant activity against Gram positive bacteria. Staphylococcus aureus was the most sensitive strain of those tested with the butanol fraction of M. marginatum (moss), with the strongest inhibition zone of 102.92% and minimum inhibitory concentration of 30 μg mL(-1).
CONCLUSION: Our findings support the use of the bryophytes in traditional medicine for burn infections because of their significant antibacterial activity.
Authors:
Meenakshi Singh; Shweta Singh; Virendra Nath; Vinay Sahu; Ajay Kumar Singh Rawat
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Publication Detail:
Type:  Journal Article     Date:  2011-03-11
Journal Detail:
Title:  Pharmaceutical biology     Volume:  49     ISSN:  1744-5116     ISO Abbreviation:  Pharm Biol     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-19     Completed Date:  2011-08-18     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  9812552     Medline TA:  Pharm Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  526-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology*
Bacterial Infections / drug therapy*
Bryophyta*
Burns / complications,  drug therapy*
Hepatophyta*
Humans
Microbial Sensitivity Tests
Plant Extracts / pharmacology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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