Document Detail

Antibacterial activity of rosin and resin acids in vitro.
MedLine Citation:
PMID:  2281306     Owner:  NLM     Status:  MEDLINE    
The antibacterial effects of rosins and resin acids were studied in vitro using three methods, disc diffusion on agar, agar dilution, and broth dilution. Rosin and some resin acids had antibacterial effects that were restricted to Gram-positive bacteria. The abietic type of acids had a more pronounced antibacterial activity than the pimaric and labdane acids when the disc diffusion method was used but there was no inhibition of growth of Gram-negative bacteria. Among the individual resin acids, dehydroabietic acid was generally the most potent, when disc diffusion on agar was used, and prediffusion increased the inhibitory effect. The composition of the pure resin acids dehydroabietic, neoabietic, and isopimaric acid did not change during the experiment, but abietic and levopimaric acid were converted into dehydroabietic acid by the addition of Müller-Hinton agar. In conclusion the old tradition of treating wounds with pitch, sap, rosin, or rosin containing tapes might therefore have some antibacterial relevance.
T A Söderberg; R Gref; S Holm; T Elmros; G Hallmans
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi     Volume:  24     ISSN:  0284-4311     ISO Abbreviation:  Scand J Plast Reconstr Surg Hand Surg     Publication Date:  1990  
Date Detail:
Created Date:  1991-03-13     Completed Date:  1991-03-13     Revised Date:  2002-11-01    
Medline Journal Info:
Nlm Unique ID:  8707869     Medline TA:  Scand J Plast Reconstr Surg Hand Surg     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  199-205     Citation Subset:  IM    
Department of Hand Surgery, University Hospital of Umeå, Sweden.
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MeSH Terms
Bacteria / drug effects*
Escherichia coli / drug effects
Klebsiella pneumoniae / drug effects
Microbial Sensitivity Tests
Pseudomonas / drug effects
Resins, Plant / pharmacology*
Staphylococcus / drug effects
Streptococcus / drug effects
Reg. No./Substance:
0/Resins, Plant; 8050-09-7/rosin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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