Document Detail


Antiarrhythmic drug therapy in the treatment of atrial fibrillation.
MedLine Citation:
PMID:  8950053     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Treatment of atrial fibrillation is often unsatisfactory because no available drug has been shown to be clearly superior for maintaining patients in sinus rhythm, and all agents have significant potential for toxicity. Selection of an antiarrhythmic drug is more likely to be based on the drug's potential for toxicity, rather than its demonstrated superior efficacy in the treatment of atrial fibrillation. Careful assessment of each patient for contraindications to individual agents and the likelihood of treatment success needs to be done before initiating antiarrhythmic therapy.
Authors:
F Jung; J P DiMarco
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  14     ISSN:  0733-8651     ISO Abbreviation:  Cardiol Clin     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-03-14     Completed Date:  1997-03-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-20     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, USA.
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MeSH Terms
Descriptor/Qualifier:
Amiodarone / therapeutic use
Animals
Anti-Arrhythmia Agents / pharmacology,  therapeutic use*
Atrial Fibrillation / drug therapy*,  etiology,  physiopathology
Clinical Trials as Topic
Electrophysiology
Flecainide / therapeutic use
Humans
Ion Channels / drug effects
Quinidine / therapeutic use
Sotalol / therapeutic use
Sulfonamides / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 0/Ion Channels; 0/Sulfonamides; 130350-52-6/ibutilide; 1951-25-3/Amiodarone; 3930-20-9/Sotalol; 54143-55-4/Flecainide; 56-54-2/Quinidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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