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Anti-thymocyte globulin induced non-cardiogenic pulmonary edema during renal transplantation.
MedLine Citation:
PMID:  22346035     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Non-cardiogenic pulmonary edema (NCPE) is a clinical syndrome characterized by simultaneous presence of severe hypoxemia, bilateral alveolar infiltrates on chest radiograph, without evidence of left atrial hypertension/congestive heart failure/fluid overload. The diagnosis of drugrelated NCPE relies upon documented exclusion of other causes of NCPE like gastric aspiration, sepsis, trauma, negative pressure pulmonary edema. We describe a 28year-old, 50 kg male with ASA risk III posted for laparoscopic renal transplantation, who developed NCPE after 4 hours of administration of rabbit anti-human thymocyte immunoglobulin (ATG). He was successfully treated with mechanical ventilatory support and adjuvant therapy. This report emphasizes that this fatal complication may occur with use of ATG.
Authors:
Beena K Parikh; Guruprasad P Bhosale; Veena R Shah
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine     Volume:  15     ISSN:  1998-359X     ISO Abbreviation:  Indian J Crit Care Med     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-02-20     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101208863     Medline TA:  Indian J Crit Care Med     Country:  India    
Other Details:
Languages:  eng     Pagination:  230-2     Citation Subset:  -    
Affiliation:
Department of Anaesthesia and Critical Care, Institute of Kidney Diseases and Research Centre and Institute of Transplantation Sciences, Civil Hospital Campus, Ahmedabad - 380 016, Gujarat, India.
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