Document Detail


Anti-mullerian hormone and cumulative pregnancy outcome in in-vitro fertilization.
MedLine Citation:
PMID:  20467803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the role of Anti-mullerian hormone (AMH) in predicting cumulative pregnancy outcome during in-vitro fertilization (IVF) treatment.
METHODS: Serum AMH levels on day 6 of ovarian stimulation were taken from 180 women undergoing IVF with or without intracytoplasmic sperm injection (ICSI). The main outcome measures were ongoing pregnancy in the fresh cycle, cumulative ongoing pregnancy and ovarian response.
RESULTS: There was a trend of higher median AMH levels in subjects achieving ongoing pregnancy in the fresh IVF cycle. The median AMH levels were significantly higher in subjects attaining ongoing pregnancy cumulatively and in subjects showing ovarian hyper-response in the stimulated cycle. Areas under the ROC curves were 0.606 and 0.792 for the prediction of cumulative ongoing pregnancy and ovarian hyper-response respectively.
CONCLUSIONS: Serum AMH concentration on day 6 of stimulation was significantly higher in subjects who achieved cumulative ongoing pregnancy in IVF compared to those who did not. Serum AMH is a reasonably good predictor of ovarian hyper-response.
Authors:
Suresh Kini; H W Raymond Li; Dave Morrell; Sue Pickering; K Joo Thong
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Publication Detail:
Type:  Journal Article     Date:  2010-05-14
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  27     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-20     Completed Date:  2011-01-28     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  449-56     Citation Subset:  IM    
Affiliation:
Assisted Conception Programme, Royal Infirmary of Edinburgh, Edinburgh, UK. suresh.kini@nhs.net
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Mullerian Hormone / blood*
Female
Fertilization in Vitro*
Humans
Pregnancy
Pregnancy Rate
Retrospective Studies
Chemical
Reg. No./Substance:
80497-65-0/Anti-Mullerian Hormone
Comments/Corrections

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