Document Detail

Anti-inflammatory effects of a special carbohydrate-whey protein cake after exhaustive cycling in humans.
MedLine Citation:
PMID:  23360676     Owner:  NLM     Status:  Publisher    
Intense exercise induces increased levels of pro-inflammatory and anti-inflammatory cytokines. Thus, the purpose of this study was to examine the effects of a special cake (consisting of carbohydrate to whey protein 3.5:1) vs an isocaloric carbohydrate cake on inflammatory markers after exhaustive cycling in humans. Nine subjects received either the experimental or placebo cake in a counterbalanced fashion using a crossover, double-blind, repeated-measures design. They performed one trial involving a 2-hour exercise on a cycle ergometer at 60-65% VO(2)max followed by a 4-hour recovery and then a second trial involving an 1-hour exercise at 60-65% VO(2)max which was increased at 95% VO(2)max. Blood samples were collected pre exercise, 30 min and 4 h post-exercise, post time Trial and 48 h post time Trial. Cakes were consumed immediately post exercise and every 1 h for the next 3 hours. The results showed that consumption of the experimental cake reduced significantly (p<0.05), 4 hours post exercise, the pro-inflammatory protein levels IL-6 and CRP compared to the control group by 50% and 46% respectively. Moreover, in the experimental cake group, the level of the anti-inflammatory cytokine IL-10 was higher by 118%, 4 hours post-exercise, compared to the control group but not statistically significant.
Efthalia Kerasioti; Dimitrios Stagos; Athanasios Jamurtas; Alexandra Kiskini; Yiannis Koutedakis; Nikos Goutzourelas; Spyros Pournaras; Aristidis M Tsatsakis; Dimitrios Kouretas
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-26
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  -     ISSN:  1873-6351     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier Ltd.
Department of Biochemistry & Biotechnology, University of Thessaly, Larisa 41221, Greece. Electronic address:
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