| Anti-glomerular basement membrane disease in an HIV-infected patient. | |
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MedLine Citation:
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PMID: 18212779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Background A 55-year-old HIV-positive male presented with gross hematuria, proteinuria, acute azotemia, and recurrent left hip septic arthritis. Anti-glomerular basement membrane (anti-GBM) antibodies were present in the patient's serum, and eosinophils were noted in his urine. Renal biopsy revealed active crescents, with linear staining of the capillary wall for IgG consistent with anti-GBM nephritis. Investigations Physical examination, blood and urine analyses, chest X-ray, CT imaging of the abdomen and pelvis, renal ultrasound, and renal biopsy. Diagnosis Anti-GBM disease. Management Owing to the presence of active HIV infection and recurrent left hip septic arthritis, a novel approach to treatment was pursued in the hope of reducing infectious consequences. The patient received steroids, intravenous immunoglobulin, rituximab, and mycophenolate mofetil. |
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Authors:
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Eric Wechsler; Tom Yang; Stanley C Jordan; Ashley Vo; Cynthia C Nast |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-01-22 |
Journal Detail:
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Title: Nature clinical practice. Nephrology Volume: 4 ISSN: 1745-8331 ISO Abbreviation: - Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-27 Completed Date: 2008-07-24 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 101261800 Medline TA: Nat Clin Pract Nephrol Country: England |
Other Details:
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Languages: eng Pagination: 167-71 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. wex1214@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Glomerular Basement Membrane Disease
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etiology* HIV Infections / complications*, diagnosis Humans Male Middle Aged |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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