Document Detail


Anti-diabetic potential of ursolic acid stearoyl glucoside: a new triterpenic gycosidic ester from Lantana camara.
MedLine Citation:
PMID:  22051701     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new stearoyl glucoside of ursolic acid, urs-12-en-3β-ol-28-oic acid 3β-D-glucopyranosyl-4'-octadecanoate and other compounds were isolated from the leaves of Lantana camara L. The structure of this new glycoside was elucidated and established by standard spectroscopic methods. In streptozotocin-induced diabetic rats it showed significant reduction in blood glucose level.
Authors:
Imran Kazmi; Mahfoozur Rahman; Muhammad Afzal; Gaurav Gupta; Shakir Saleem; Obaid Afzal; Md Adil Shaharyar; Ujjwal Nautiyal; Sayeed Ahmed; Firoz Anwar
Publication Detail:
Type:  Journal Article     Date:  2011-10-24
Journal Detail:
Title:  Fitoterapia     Volume:  83     ISSN:  1873-6971     ISO Abbreviation:  Fitoterapia     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-13     Completed Date:  2012-04-26     Revised Date:  2012-09-14    
Medline Journal Info:
Nlm Unique ID:  16930290R     Medline TA:  Fitoterapia     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  142-6     Citation Subset:  IM    
Copyright Information:
Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.
Affiliation:
Siddhartha Institute of Pharmacy, Uttarakhand, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Glucose / drug effects
Diabetes Mellitus, Experimental / drug therapy*
Glucosides / chemistry,  pharmacology*
Hypoglycemic Agents / chemistry,  pharmacology*
Lantana / chemistry*
Molecular Structure
Plant Leaves / chemistry
Rats
Sterols / chemistry,  pharmacology*
Triterpenes / chemistry,  pharmacology*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Glucosides; 0/Hypoglycemic Agents; 0/Sterols; 0/Triterpenes; 77-52-1/ursolic acid
Comments/Corrections
Erratum In:
Fitoterapia. 2012 Sep;83(6):1151

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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