Document Detail


Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody.
MedLine Citation:
PMID:  8042617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated anti-annexin V antibody (aANX) in patients with systemic lupus erythematosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with beta 2-glycoprotein 1 (GPI)-dependent aANX. The positivity of aANX was higher in patients with aCL (19%) and LA/aCL (50%) than in those without LA/aCL (10%). From these results, it is concluded that aANX is an autoantibody closely related to LA/aCL, and can be a possible new risk marker for thrombosis.
Authors:
J Matsuda; N Saitoh; K Gohchi; M Gotoh; M Tsukamoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hematology     Volume:  47     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1994-08-19     Completed Date:  1994-08-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  56-8     Citation Subset:  IM    
Affiliation:
Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Annexin A5 / immunology*
Antibodies / blood*
Antibodies, Anticardiolipin / blood*
Humans
Lupus Coagulation Inhibitor / blood*
Lupus Erythematosus, Systemic / blood,  immunology*
Chemical
Reg. No./Substance:
0/Annexin A5; 0/Antibodies; 0/Antibodies, Anticardiolipin; 0/Lupus Coagulation Inhibitor
Comments/Corrections
Comment In:
Am J Hematol. 1995 Sep;50(1):68   [PMID:  7668234 ]

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